Postdoctoral Scholar Fellowship Trainee in Biology & Biological Engineering
Profile
Education:
BS, Biological Sciences and Russian Studies, Carnegie Mellon University, 2014 PhD, Immunology, University of Chicago, 2022
Biosketch:
Brendan is studying how the T-lineage developmental program changes over the lifespan of an individual—specifically how quantitative dosage changes to individual transcription factors within the gene regulatory network cause characteristic age-associated shifts in potential for thymocytes to give rise to ILCs and innate-like γδT cells. He is interested in studying the modular and combinatorial structure of GRNs more broadly, and how different pathways interact to determine cell lineage fates and functional states within the immune system. Brendan previously worked on defining the antigen presentation pathways involved in priming anti-tumor immune responses as a PhD student in the lab of Justin Kline at the University of Chicago, and he considers himself to be a once and future dendritic cell biologist.
